Once it seemed as though penicillin and other antibiotics had won humanity a lasting victory over harmful bacteria. But now hardier bugs, resistant to most common classes of antibiotics, are emerging-with potentially catastrophic consequences.

This is the frightening, all-too-plausible, premise of bestselling author Daniel Kalla's latest thriller, RESISTANCE (A Tor mass market original; $10.99; May 2, 2006.) An Emergency Room physician, Dr. Kalla knows first-hand the dangers of antibiotic resistance, and by weaving scientific facts with unforgettable characters and a taut storyline, he brings to life an extraordinary thriller that will have readers washing their hands diligently-and lying awake far into the night.

Daniel Kalla burst onto the literary scene in 2005 with Pandemic (Tor mm 2005), a chilling novel that sprang from his experience with a potential SARS epidemic that threatened Vancouver, Canada in 2003. It received wide praise from critics and colleagues alike, and became a national bestseller. Now, Daniel Kalla explores the very real world of superbugs, unethical pharmaceutical companies, and antibiotic resistance in his latest entertaining, and utterly thought-provoking, thriller.

When Dr. Catalina Lopez of the Center for Disease Control first receives a report of a lethal new superbug immune to all known antibiotics, she realizes that she has a major health crisis on her hands. An ultra-resistant form of group A strep is spreading like wildfire throughout hospitals and emergency rooms in Seattle and the Pacific Northwest. Doctors, lacking any effective way to combat the infection, can do nothing but stand by and watch their patients die, one after another.

Dr. Graham Kilburn, an infectious disease specialist in Vancouver, is one such doctor. Desperate to contain the spread of the new superbug, he joins forces with Lina as they try to find some way to halt the growing epidemic.

Meanwhile in Portland, a homicide cop's investigation into a double murder leads him to suspect that someone might be deliberately spreading drugs tainted with a killer germ, while in Philadelphia, a young scientist's dreams are threatened when potentially devastating side effects arise during the testing of her new ultra-effective antibiotic.

This new superbug-and its only antidote-thrusts the four individuals into a deadly game of cat and mouse, as each begins to understand that man, not nature, has created this deadly resistance. But what they don't realize is that shadowy forces are conspiring to spread the disease on purpose...and they will stop at nothing to avoid exposure.

-- From TOR Publishing